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about the coalition


Winner of the 2008
Consumer Health World Award
The most up-to-date
source of cancer clinical
trial information.



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About the Coalition

Programs & Services

TrialCheck®

TrialCheck®, winner of 2008 Consumer Health World Award "Best in Show," is the country’s most up-to-date source of cancer clinical trial information. This free on-line navigation and matching system links patients, caregivers and the health care community to unbiased cancer clinical trials.

Introduced in 2001 by the Coalition, TrialCheck® is the most frequently updated searchable database of cancer clinical trials. TrialCheck® maps relevant cancer trials to patients homes by filtering information such as type of cancer, zip code and other criteria.

TrialCheck® is a highly flexible resource that has been customized to include trials defined by specific disease site, geographic area, or performance site/hospital.

Learn more about:

TrialCheck® Data

The system pools together information from multiple databases for all federally registered cancer clinical trials, both publicly and privately sponsored. Real-time daily quality control processes ensure that the information is accurate and reliable.

TrialCheck® Phone Support

Telephone assistance in finding a cancer clinical trial using TrialCheck® is available at 1-877-227-8451 via collaboration with the American Cancer Society, which uses TrialCheck® as their exclusive search engine for all cancer clinical trials.

TrialCheck® Demo

TrialCheck® Site Integration and Report Capabilities

The Coalition offers to tailor the TrialCheck® software and trial data so that it can interface with other organizations’ specific cancer clinical research activities.

Clients include public health departments, health care technology companies, health care practices and institutions, advocacy and other nonprofit organizations, and pharmaceutical and biotech companies, all whom share the same altruistic mission: to streamline and accelerate physician and patient enrollment into cancer clinical trials.

Tailored products include:

  • Technological Integration - TrialCheck® can be customized with specific information displays and user interfaces to include geographic location, hospital or facility, disease and protocol. It can be integrated into a Web site as well as an existing software system.
  • Clinical Software - TrialTracker electronically tracks clinical trial screening, eligibility and enrollment for patients being served.
  • Reporting Services - Ability to run automated reports on trials within the database such as by cooperative group, hospital/institution/practice, type of cancer, drug, etc. providing a full picture of the cancer clinical trial landscape.

TrialTracker, Web-based system
Track Local Screening, Eligibility and Enrollment at the Patient Level

TrialCheck®'s TrialTracker helps to thoroughly monitor your patients. It is a cancer clinical trial screening log that enables healthcare professionals to track cancer clinical trial screening, eligibility, and enrollment of patients participating in studies at a specific performance site or hospital.

TrialTracker utilizes TrialCheck's screening questionnaire to easily identify trials that may be appropriate for each individual patient. This online tool allows healthcare professionals to keep a log of patients that are screened for studies at a specific performance site or hospital. TrialTracker records if a patient is eligible or not eligible for a study. In addition, it captures if the patient does or does not enroll in a specific study.

Easy Access to Patient Information

TrialCheck® Collaborators

Questions and Answers

1) What is TrialCheck®?

TrialCheck® is an Internet-based cancer clinical trial navigation and matching system of all federally registered cancer clinical trials, whether publicly or privately funded. It is considered to be one of the most reliable cancer clinical trial services in the U.S. and is the exclusive clinical trial search engine option for the American Cancer Society and The Leukemia & Lymphoma Society.

TrialCheck® was created by the non-profit Coalition of Cancer Cooperative Groups to support patients, caregivers, health care professionals, advocates and researchers in exploring cancer clinical trials as a potential cancer treatment option.

2) Where does the TrialCheck® clinical trial information come from?

It received a prestigious Bronze-level certification award from the NCI’s cancer Biomedical Informatics Grid (caBIG) network as one of the few systems capable of supporting NCI’s efforts to fully integrate the nation’s cancer clinical trial databases.

3) How does TrialCheck® work?

4) Are there other ways to gain access to TrialCheck®?

5) Why is TrialCheck® important for patients with cancer?

Cancer clinical trials provide state-of-the-art, life-saving care, yet many cancer patients are not aware of their importance as a potential treatment option, especially at the time of their diagnosis and throughout the treatment process when decisions about their cancer treatment are being made. Clinical trials are often mistakenly thought of as a last resort when all other options have failed the patient. Studies have shown that as many as 250,000 U.S. cancer patients would be willing and clinically eligible to participate in clinical trials if they were made aware of the option (Journal of Clinical Oncology, Mar 1 2003: 830-835). By providing easier access to clinical trial information, TrialCheck® gives patients knowledge about an essential treatment option that is often overlooked, and guides them to hospitals and physicians that provide cancer clinical trials.

By supporting cancer clinical trial enrollment, TrialCheck® also helps drive the research engine that produces virtually all cancer treatment advances.

6) How does TrialCheck® "mainstream" information for patients?

TrialCheck® gives patients access to the same clinical trial information that is available to physicians, thereby enabling doctors and patients to make treatment decisions together.

7) There are other cancer clinical trial databases accessible via the Internet. Why do patients, caregivers, advocates and others in the cancer treatment community need TrialCheck®?

Many of the cancer clinical trial resources currently available online are limited in their ability to help patients, caregivers, advocates and the general public. Originally developed for researchers, they can be difficult to navigate and may require a fairly sophisticated knowledge of medical terminology. The U.S. government’s main registry lists trials for all diseases, not only cancer, and lacks the level of detail needed to match trials to a cancer patient’s particular disease and treatment history.

The comprehensive information in TrialCheck® is considered to be the most reliable in the industry. It is the only nationwide system updated in real time. A team of clinical experts review the precise eligibility requirements for all trials before they enter the database to ensure that search queries by and for patients will produce accurate and reliable customized trial lists.

As a free public service, TrialCheck®'s primary goal is to serve the best interest of the cancer patient; therefore, the trial information it contains is comprehensive and unbiased. Its priority is to provide the most relevant trials available per patient regardless of whether the study is publicly or privately funded.

8) How is TrialCheck® funded?

TrialCheck® is a free public service to support patients, caregivers, health care professionals and advocates in exploring cancer clinical trials as a potential treatment option at time of diagnosis and throughout the treatment process. The Coalition, a non-profit 501(c)(3) service organization, receives charitable funding for TrialCheck® and other programs and services through grants and sponsorships from corporations and foundations, and membership dues from the cooperative groups. In addition, the organization offers to tailor the TrialCheck® software for a fee so that it can interface with other organizations’ specific cancer clinical research activities.

9) Explain the connection between TrialCheck®'s non-profit status and its unbiased information.

10) Does TrialCheck® offer any services to health care professionals, or is it strictly for patients and caregivers?

The free access to TrialCheck® enables oncology health care providers to quickly determine whether a patient may be a candidate for a clinical trial, both within their own institutional setting, or if there is no trial match for a patient at their own hospital/practice/institution, to find trials with other oncologists at medical facilities nearby. Thousands of oncology clinicians are registered users of TrialCheck® because it has the critical information that is needed to identify trials for their patients.

A diagnosis of cancer is often made by a general physician, who will refer the patient on to an oncologist for treatment. For referring physicians, the free TrialCheck® searching provides a similar service, the ability to search within the oncology research network to find accurate, up-to-date information so that newly diagnosed patients can be referred to an oncologist nearby who is offering a trial that may be an appropriate match for the patient.

The Coalition offers to tailor the TrialCheck® software for a fee so that it can interface with other organizations’ specific cancer clinical research activities. Through Technical Integration TrialCheck® can be integrated and customized to trials within the hospital’s geographic region, the specific facility, and specific diseases and protocols. It can be integrated into a hospital’s Web site as well as into an existing software system. With Clinical Software, professionals can electronically track clinical trial screening, eligibility and enrollment activity information for their patients. And with Reporting Services, professionals can run automated reports on trials within the database such as by cooperative group, hospital/institution/practice, type of cancer, drug, etc.

11) Why is TrialCheck® an Internet-based system?

More than 73 percent of American adults have access to the Internet and research shows that 80 percent of those have searched for health care information (66 percent for a specific disease or medical problem and 51 percent for certain medical treatments or procedures). Of the 80 percent, five to six percent are so-called acute ePatients, along with their caregivers. These users – people facing new medical challenges – make up over 50 percent of medical Internet traffic.* These patients go online every day and conduct exhaustive searches over hundreds of hours. An Internet-based system ensures that cancer clinical trial information is always accessible and available to these patients.

There are currently more than 7,000 cancer clinical trials federally registered in the national database. The information about clinical trials is highly dynamic both in terms of studies opening to patient enrollment and closing when enrollment is completed. In addition, information about the hospital and oncology practices where clinical trials are available is constantly changing. Only an online, Internet-based service can accommodate this information and be kept accurate.

* Source: Pew Internet Life Project 2006 and 2000, April 2006